As we’ve seen in previous posts, the world of diagnostic test development is quite complicated. In addition to the multiple ways a diagnostic test can get to market, there are many different types of organizations that develop and run tests. Take a look at this zoomed-in view of the Map of Biomedicine:Read More
Up at 5AM: The 5AM Solutions Blog
According to the Personalized Medicine Coalition (PMC), personalized medicine is "... the tailoring of medical treatment to the individual characteristics of each patient…to classify individuals into subpopulations that differ in their susceptibility to a particular disease or their response to a specific treatment..." [emphasis ours]. It's an exciting proposition that could -- in the long run -- reduce health care costs overall, and offer individuals the best available treatments for them as people instead of the best available treaments for a disease.
So what's stopping us? There are lots of reasons that a personalized approach to medicine isn't yet part of the mainstream, but here is a roundup of 3 things standing between you and customized medical treatments.Read More
Experts around the globe agree that most skin cancers are preventable. They disagree, however, on what skin cancer prevention looks like.
It’s been a busy June. The air is thick with buzz about healthcare data, information and engagement from both the business and consumer sides of the healthcare coin. During the first month of summer 5AM and our partners and customers saw, heard, read , and -- in some cases -- ushered in signs of momentum toward patient-centered care. Here’s our short list:
DIA kicked off its 50th Annual Meeting in San Diego, yesterday, where the theme is "Celebrate the Past - Invent the Future." The future (or part of it, anyway) seems to have arrived at DIA 2014 where, from keynote to closing, patient advocates have a prominent seat at the head of the table; a table previously reserved for health care professionals. It makes us hopeful: is the personalized, patient-centered future here?
Yesterday, at Health Datapalooza, United States CTO, Todd Park, announced that the U.S. Department of Health and Human Services (HHS) and the Centers for Medicare & Medicaid Services (CMS) had launched initiatives that make tons of much-requested — but hard to get — health data accessible to the public.
Physicians currently rely on a variety of techniques to diagnose disease, from imaging to physical examinations to laboratory tests. Personalized medicine, which allows targeted therapies to be confidently prescribed, i.e. getting the right medication to the right patient at the right time, relies on a diagnosis that takes into account the molecular characteristics of the patient and the disease.
The future of optimal health and cost effective, efficient care is dependent on the development of personalized medicine. Historically, scientific discovery and delivery of care has been developed from a one dimensional view of patients that assumed all individuals with a disease are the same – a one size fits all diagnosis and treatment regime which, over the past several decades, has failed to produce superior therapies and health outcomes.
Zydeco is defined by the integration of far afield music genres, purportedly taken from a french saying “I’m so poor, I can’t afford any salt meat for the beans." The news of FDA’s approval of Kalydeco on February 1, 2012 illustrates the conundrum of where we are in the decades long march towards personalized medicine. There is much to celebrate. It’s music to the ears of many that the we are now beginning to attack the root cause cystic fibrosis rather than the symptoms. And more importantly for all the other diseases with genetic causes, we’ve been able to actually design a drug that fixes a genetic defect. But there isn’t a ton of pork that would make our biomedical ecosystem beans taste great.