Up at 5AM: The 5AM Solutions Blog

5AM Solutions CSO Will FitzHugh Wins Executive Management Award

Posted on Tue, Mar 10, 2015 @ 03:00 PM

Last night, 5AM Solutions' Chief Science Officer Will FitzHugh was among the honorees at SmartCEO magazine's Washington Executive Management Awards. If you haven't worked with him directly, you might know Will from this blog. Most recently, he was the author of the Map of Biomedicine series (stay tuned for an upcoming ebook...) and he has also written about newborn screening and big data.

Read More

Tags: Big Data, map of biomedicine, 5AM, newborn screening

5AM's Will FitzHugh is Speaking at "Newborn Screening in Morocco"

Posted on Thu, Dec 04, 2014 @ 03:00 PM

I'm very excited about a workshop I am attending next week. I've been invited to speak at Newborn Screening in Morocco in a city called Fes. After launching its first newborn screening pilot program in 2011, Morocco is starting to more regularly test newborns for a variety of conditions. An example  is Phenylketonuria (PKU), which is a rare genetic disorder that can cause serious health problems, but can be controlled with a modified diet.
Read More

Tags: 5AM, newborn screening

Cannabinoids Offer Hope to Brain Cancer and HIV Patients

Posted on Thu, Nov 20, 2014 @ 03:00 PM

To date, 23 states and the District of Columbia have enacted legislation to make cannabis available to people with medical conditions that can be alleviated using the drug. Many people understand the laws in terms of offering compassionate pain relief and appetite stimulation for people suffering devastating illnesses like cancer and HIV/AIDS.

Read More

Tags: cancer, 5AM, HIV

Automated Testing Yields Better (and Safer) Software

Posted on Thu, Sep 18, 2014 @ 03:30 PM

On September 26, 1983, three weeks after the Soviet Union shot down a Korean Airlines passenger jet carrying a US congressman and raising Cold War tensions to new heights, Lt.  Col. Stanislav Petrov was quietly sitting at his desk in a bunker near Moscow when he received some bad news.  Satellites had detected five ICBMs coming from the United States and they were headed his way.  

Read More

Tags: software development, 5AM, software

Liquid Biopsy - Curing Cancer from the Inside Out, Ctd.

Posted on Thu, Aug 14, 2014 @ 03:00 PM

Last week, we did a post on curing cancer at the gene-level.  But what about using genes to diagnose cancer? A feature story in the MIT Technology Review looks at research happening at Johns Hopkins University on that very possibility.

Read More

Tags: cancer, Genomics, 5AM, diagnostics, Cure

Newborn Screening is Personal

Posted on Tue, Aug 12, 2014 @ 03:15 PM

It's no secret that we human beings will go to great lengths to keep our families safe and healthy. In the late 1940s, Dr. Robert Guthrie, a cancer doctor, learned that his son, John had mental retardation. About a decade later, after switching his focus to finding the causes of mental retardation, Dr. Guthrie's niece was born with phenylketonuria (PKU), a genetic disorder that prevents the body from metabolizing the amino acid phenylalanine. Untreated, PKU can lead to mental retardation. 

Read More

Tags: genetic testing, 5AM, newborn screening

Long Commute? Update Your Software.

Posted on Thu, Jul 24, 2014 @ 02:45 PM

5AMers think about software. A lot.

Read More

Tags: Working at 5AM, software development, 5AM, Life at 5AM, software

Practicing Our Craft - Developing Great Software

Posted on Tue, Jul 22, 2014 @ 12:30 PM

The clock shows a minute past noon. The stragglers of a steady stream of 5AMers finish sneaking in the conference room door and quickly take their seats. Someone dims the lights while another finishes pulling the shades. A hush comes over the room. “Everybody ready?” Nods answer. A mouse cursor clicks the play button. The frozen bespectacled figure on the projector screen comes to life. In a stern voice, he declares, “Integrated tests are a scam – a self-replicating virus that invades your projects! It threatens to destroy your codebase, to destroy your sanity, to destroy your life.” Another 5AM Tech Talk begins…

Read More

Tags: Working at 5AM, software development, 5AM, Life at 5AM

Advancing Biobanks through Continued Education at BioCoR

Posted on Tue, Apr 01, 2014 @ 10:18 AM

It can seem like biobanking is a ‘cold black box’ process. Samples are processed, labeled stored and retrieved. For many involved in biobanking, it is not clear that processing and storing a biospecimen must be based on core scientific principals in order for the biospecimen to be useful for downstream applications. Biobanking also requires in infrastructure: equipment, biospecimen management systems that may include labels, label readers, and information systems for linking important data about the biospecimen with the actual specimen.

Read More

Tags: biobanking, 5AM, Advancing Biorepositories with Data Science

The 3rd Annual Disruptive Innovation to Advance Clinical Trials Event

Posted on Mon, Aug 26, 2013 @ 10:26 AM

5AM Solutions is proud to be a sponsor at the 3rd Annual Disruptive Innovation to Advance Clinical Trials Event taking place September 19 and 20th at the The Fairmont Copley Plaza in Boston, MA. As part of our participation in this conference, we are excited to offer a 25% registration discount to those who would like to join us at the event. Use the code "5AM" at the end of the registration process to receive your discount. 

Read More

Tags: clinical trials, Innovations, Craig Lipset, Boston, Conference, Advance, Pfizer, 5AM, The Conference Forum


Diagnostic Tests on the Map of Biomedicine


Download the ebook based on our popular blog series. This free, 50+ page edition features updated, expanded posts and redesigned, easier-to-read maps. 

FREE Biobanking Ebook

Biobanking Free Ebook
Get this 29 page PDF document on how data science can be used to advance biorepositories.

 Free NGS Whitepaper

NGS White Paper for Molecular Diagnostics

Learn about the applications, opportunities and challenges in this updated free white paper. 

Recent Posts